Clinical characteristics of disseminated herpes zoster: a single centre experience

등록일 2017.12.21 파일확장자어도비 PDF (pdf) | 1페이지 | 가격 1,000원
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발행기관 : 대한피부과학회 수록지정보 : 프로그램북(구 초록집) / 69권 / 2호
저자명 : ( Hak-jun Kim ) , ( Tae-wook Kim ) , ( Hyun-joo Lee ) , ( Sung-min Park ) , ( Hyunju Jin ) , ( Hyang-suk You ) , ( Woo-haing Shim ) , ( Gun-wook Kim ) , ( Hoon-soo Kim ) , ( Hyun-chang Ko ) , ( Byung-soo Kim ) , ( Moon-bum Kim )

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Background: Cutaneous dissemination of herpes zoster mainly occurs in immunocompromised patients. There are few reports focused on clinical characteristic and underlying disease of disseminated herpes zoster (DHZ) in Korea. Objectives: To describe clinical characteristics of DHZ, and to investigate the clinical difference between immunocompromised and immunocompetent groups. Methods: The patients diagnosed with DHZ in Department of Dermatology, Pusan National University Hospitals (Busan and Yangsan) from 2007 to 2017, were retrospectively reviewed. Results: A total of 26 patients were enrolled. The mean age was 63.3 years (range 35-82), and the male to females ratio was 4.2. Twenty (77%) patients had underlying disease; hypertension (46%) was most common, followed by malignancy (35%), and diabetes (27%). Fifteen (57.7%) patients were immunocompromised. Lumbar dermatome was most commonly involved (42.3%), and the average interval of dissemination was 2.6 days. The incidence of postherpetic neuralgia was higher in patients with DHZ, compared with ordinary herpes zoster (n=401, 30% versus 17.5%). There was no significant difference in involved area, treatment duration, and interval of dissemination between immunocompromised and immunocompetent group. (p>0.05) Conclusion: About half of patients with DHZ were immunocompromised. However, no clinical difference was observed between immunocompromised and immunocompetent groups.

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Clinical characteristics of disseminated herpes zoster: a single centre experience
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