경남 일부지역 폐경 전·후 여성들의 골밀도와 생화학지수들과의 관련성에 관한 비교연구

저작시기 2017.08 |등록일 2017.09.27 파일확장자어도비 PDF (pdf) | 12페이지 | 가격 6,000원
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서지정보

발행기관 : 동아시아식생활학회 수록지정보 : 동아시아식생활학회지 / 27권 / 4호
저자명 : 박미영, 김성희

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ABSTRACT
서론
연구 방법
결과 및 고찰
요약 및 결론
REFERENCES

영어 초록

This study was carried out to compare the relationship between biochemical indices and bone mineral density (BMD) in 50 pre-menopausal and 50 post-menopausal women. The subjects were divided into normal and risk groups according to their bone status, as determined by T-scores of the lumbar spine and femur. The average T-score of the lumbar spine was higher (p<0.05) in pre-menopausal women (0.42±0.18) than post-menopausal women (—0.08±0.21). Serum levels of HDL-cholesterol, P, and Fe were significantly higher in the risk group than the normal group in pre-menopausal women (p<0.05). Serum levels of total protein, globulin, alkaline phosphatase (ALP), and osteocalcin were lower in the risk group than the normal group, whereas the level of estrogen was higher in the normal group than the risk group in post-menopausal women (p<0.05). In pre-menopausal women, P was positively correlated with Ca (p<0.01), and ALP was positively correlated with osteocalcin (p<0.01) and parathyroid hormone (PTH) (p<0.05). Further, insulin-like growth factor-Ⅰ (IGF-I) was negatively correlated with the vitamin 25(OH)D<SUB>3</SUB> and vitamin K (p<0.05). In post- menopausal women, the Ca was positively correlated with vitamin 25(OH)D<SUB>3</SUB> (p<0.05) and vitamin K (p<0.01), and P was positively correlated with vitamin K (p<0.01), Ca (p<0.01), and IGF-I (p<0.05) and negatively correlated with PTH (p<0.05). IGF-I was negatively correlated with PTH (p<0.01) and estrogen (p<0.05), and ALP was positively correlated with osteocalcin (p<0.01) and negatively correlated with vitamin K and estrogen (p<0.05). In pre-menopausal women, the lumbar spine BMD was positively correlated with vitamin K level (p<0.01) and negatively correlated with P level (p<0.05). In post-menopausal women, the femur BMD was positively correlated with estrogen level and negatively correlated with PTH leves (p<0.05). These results suggest that vitamin K and P levels are associated with bone health in pre-menopausal women, and estrogen and PTH levels are associated with bone health in post-menopausal women.

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