GO에 의해 유도된 培養脊髓感覺神經細胞독성에 대한 鎭肝熄風湯의 방어효과
(주)코리아스칼라
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- 2016.04.01
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- 2003.08
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서지정보
ㆍ발행기관 : 한국전통의학연구소
ㆍ수록지정보 : 한국전통의학지 / 13권 / 1호
ㆍ저자명 : 박광수, 이호승, 김인수, 강길성, 김인규, 김인섭, 류도곤
영어 초록
To evaluate the effect of Jingansikpungtang water extract on cultured mouse spinal sensory neuron which was inhibited by glucose oxidase(GO)-induced cytotoxicity, NR assay and TBARS assay for lipid peroxidation were carried out after the cultured mouse spinal sensory neuron were pre-incubated with various concentrations of Jingansikpungtang water extract for 3 hours prior to exposure of GO. GO, a oxygen radical, decreased the survival rate of the cultured mouse spinal sensory neuron cells on NR assay. Jingansikpungtang water extract have efficacy of decreasing lipid peroxidation increasing by GO in cultured mouse spinal sensory neuron. From above the results, it is concluded that Jingansikpungtang has marked efficacy as a treatment for the damages caused in the GO-mediated oxidative process..
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