Poster : P-114 ; Atypical pleural fluid profiles in tuberculous pleural effusion: sequential changes compared with parapneumonic and malignant pleural effusions

저작시기 2015.01 |등록일 2016.01.16 파일확장자어도비 PDF (pdf) | 1페이지 | 가격 1,000원
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발행기관 : 대한결핵 및 호흡기학회 수록지정보 : 대한결핵및호흡기학회 추계학술발표초록집 / 120권
저자명 : 김창호 , 이소연 , 이용대 , 유승수 , 이신엽 , 차승익 , 박재용 , 이재희

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Objective: Although tuberculous pleural effusion (TPE) is commonly characterized by lymphocytic-predominance and high adenosine deaminase (ADA) levels, it may present neutrophilic-predominance or low ADA levels, which are more commonly found in parapneumonic effusion (PPE) or malignant pleural effusion (MPE), respectively. A few studies observed that atypical pleural fluid profiles of these TPEs may resolve at follow-up thoracentesis. However, limited data are available comparing sequential pleural fluid changes between TPE and PPE or MPE. Methods: TPE, PPE, and MPE patients who underwent sequential thoracentesis were retrospectively reviewed. The sequential changes of pleural fluid profiles were compared between neutrophilic TPE and PPE, and lymphocytic TPE and MPE with low ADA levels, respectively. Results: 23 TPEs (16 neutrophilic, 7 lymphocytic), 72 neutrophilic PPEs, and 18 lymphocytic MPEs were included. A sequential shift to lymphocytic-exudates occurred significantly more often in TPEs than in PPEs. Initial and follow-up ADA levels in TPEs with lymphocytic shift were significantly higher than those in PPEs with lymphocytic shift. ADA levels in TPEs with initial lymphocytic-exudates and low ADA levels significantly increased at follow-up thoracentesis. For TPEs and MPEs with initial lymphocytic-exudates and ADA levels <40 U/L, the frequency of effusion with ADA levels ≥40 U/L at the second thoracentesis was significantly higher in TPE. Conclusion: Follow-up thoracentesis may provide useful information for clinical decision-making in suspected atypical TPE cases.

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      Poster : P-114 ; Atypical pleural fluid profiles in tuberculous pleural effusion: sequential changes compared with parapneumonic and malignant pleural effusions
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