P584 : Treatment of classic Kaposi`s sarcoma showing a discretely scattered distribution with intralesional vinblastine injections

저작시기 2015.01 |등록일 2015.06.15 파일확장자어도비 PDF (pdf) | 1페이지 | 가격 1,000원
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발행기관 : 대한피부과학회 수록지정보 : 프로그램북(구 초록집) / 67권 / 1호
저자명 : ( Bo Ri Kim ) , ( Jung Tae Park ) , ( Sang Young Byun ) , ( Soon Hyo Kwon ) , ( Chang Hun Huh )

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Kaposi’s sarcoma (KS) is a rare angioproliferative disease related to human herpesvirus 8 (HHV-8). There are 4 clinical types of KS: classic KS (CKS), endemic African KS, AIDS-related KS, and iatrogenic posttransplantation KS. The treatment options of CKS vary depending on the clinical feature such as age, distribution, tumor depth and etc. So, the treatment must be tailored to the individuals. A 58-year-old Korean woman presented with a 5-year history of a skin lesion on the chin. Since that time of the initial lesion appeared, new skin lesions had developedslowly on the upper and lower extremities. Her past medical history was insignificant except for dyslipidemia on medication, and she was immunocompetent. After a skin biopsy and imaging workup, we diagnosed this case as a discretely scattered CKS without visceral involvement. Although the patient had multifocal lesions on head and limbs, the total number and size of lesions had no change in the recent 3 months. To minimize considerable complications of systemic chemotherapy, we decided to treat with intralesional vinblastine administration. Our patient showed dramatic response after only one cycle of the intralesional vinblastine injections without any serious side effects and had no additional lesions under the outpatient follow-up. We suggest that the intralesional vinblastine injection is one of the effective treatments alternative for relatively stable disseminated CKS.

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      P584 : Treatment of classic Kaposi`s sarcoma showing a discretely scattered distribution with intralesional vinblastine injections
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