[Disease Review] Cervical Intraepithelial Neoplasia(CIN, 자궁경부상피내 종양)

소개글

경북대학교 의과대학/의학전문대학원 PK 실습 중 작성한 Disease Review입니다.
Cervical Intraepithelial Neoplasia, 자궁경부 상피내 종양에 대해 작성하였습니다.

목차

1. Disease Review : CIN – Introduction
2. Disease Review : CIN – Pathogenesis
3. Disease Review : CIN – Classification
4. Disease Review : CIN – Screening and Diagnosis
5. Disease Review : CIN – Treatment
References

본문내용

Criteria
- Cellular immaturity/disorganization, nuclear abnormality & increased mitotic activity
- CIN 1 (Mild dysplasia)  lower 1/3
- CIN 2 (Moderate dysplasia)  middle 1/3
- CIN 3 (Severe dysplasia & CIS)  upper 1/3

<중 략>

Pathogenesis
2) Immunosuppression
- HIV infection, Immunosuppressive therapy
3) Cigarette smoking
- Cigarette smoking and HPV infection have synergistic effects on the development of CIN
4) Herpes simplex virus and chlamydia

참고 자료

Isinga RP, Glass AG, Rush BB. Diagnoses and outcomes in cervical cancer screening: a population-based study. Am J Obstet Gynecol 2004; 191:105.
Centers for Disease Control and Prevention, Workowski KA, Berman SM. Sexually transmitted diseases treatment guidelines, 2006. MMWR Recomm Rep 2006; 55:1.
Jason D Wright, Barbara Goff. Cervical intraepithelial neoplasia: Terminology, Incidence, pathogenesis, and prevention. UpToDate. 2014
Prof.홍대기. Lecture note : Intraepithelial Disease of the Cervix, Vagina and Vulva