[생명과학] The production of recombinant pharmaceutical proteins in plants
- 최초 등록일
- 2004.12.24
- 최종 저작일
- 2004.12
- 20페이지/ MS 파워포인트
- 가격 2,000원
목차
1.The production of recombinant pharmaceutical proteins in plants
2.Genetic Modification
3.Comparison of production systems for recombinant human pharmaceutical proteins
4.Recombinant proteins expressed in plants
5.Genetic aspects of molecular farming in plants
6.Plant-expression hosts
7.Acceptability
8.Conclusion
본문내용
(1)Tobacco production systems
* Tobacco is the most widely used species for the
production of recombinant pharmaceutical
proteins
* Advantages
- the mature technology for gene transfer &
expression
- the high biomass yield
- the potential for rapid scale-up
- availability of large-scale infrastructure for
processing
* Chloroplast transgenic system
- produced by introducing DNA into the chloroplast
genome
- advantage : -the high transgene-copy number
-the absence of position effects
-transgene silencing
-accumulation of recombinant
proteins in the chloroplast
- disadvantage:-plastids do not carry out
glycosylation
-chloroplast transformation outside
the solanaceae still present a
formidable technical challenge
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