글리벡에 대한조사

소개글

글리벡에 대한 조사입니다.

목차

글리베은 어떤약인가
치료가능한 질환
글리벡의 작용기전
부작용
가격
연구방향

본문내용

Glivec –글리벡(Glivec, imatinib, STI571) - tyrosine kinases inhibitor(FDA 승인 2001.5) <스위스 (Novatis) 제약회사>

A signal transduction inhibitor, Glivec interferes with the pathways that signal the growth of some tumour cells, targeting the activity of tyrosine kinases enzymes, which play an important role in certain cancer cells.

Gleevec® (imatinib mesylate) film-coated tablets contain imatinib mesylate equivalent to 100 mg or 400 mg of imatinib free base. Imatinib mesylate is designated chemically as 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-phenyl]benzamide methanesulfonate and its structural formula is

참고 자료

http://www.glivec.com
Sawyers CL. N Engl J Med. 1999;340:1330-1340.
Faderl S, et al. Ann Intern Med. 1999;131:207-219.
Pasternak G, et al. J Cancer Res Clin Oncol. 1998;124:643-660.
Melo JV. Blood. 1996;88:2375-2384
http://bric.postech.ac.kr